Synthetic polymers include polyethilene glycol (PEG), a water-soluble biocompatible polymer with good drug-carrying capacity polyvinyl alcohol (PVA), a water-soluble biocompatible polymer polyvinylpyrrolidone (PVP), a water-soluble polymer with high biocompatibility polycaprolactone (PCL), a biocompatible and biodegradable polymer polylactic acid (PLA), a biocompatible, biodegradable polymer that is often used in drug delivery applications or polyethyleneimine (PEI), a cationic polymer with good drug-carrying capacity and ability to evade the immune system. ![]() The amino acid characters of gelatin were identified as glycine (13.57%) and proline (1.62%) for bovine gelatin and glycine (0.51%) and proline (0.09%) for porcine gelatin. The FTIR spectrum of bovine gelatin shows the presence of amide A, amide I, amide II and amide III groups. Therefore, bovine gelatin is specifically capable of substituting porcine gelatin for application in the pharmaceutical field. The physico-chemical characters of bovine gelatin resulting from isolation and bovine gelatin standards are in conformity with porcine gelatin standards and meet the requirements of SNI 06-3735-1995 and GMIA. Gelatin confirmed by the physico-chemical characters, FT-IR and analysis amino acid with HPLC.The results showed that the yield of bovine gelatin was 4.33%. Ossein is hydrolyzed by gradual heating at 65, 75, and 85oC. Bovine and porcine bones were soaked in 5% HCl for 10 days and every 2 days a HCl solution was replaced to get ossein. ![]() This study aims to produce gelatin from femur bones of bovines with acid hydrolysis and their characteristics compared to standard gelatin of bovine and porcine. The similar physical appearance between bovine and porcine gelatin causes an issue for some communities like a Muslim due to awareness of halal food. Gelatin has been widely used as an additive in food industry pharmaceutical, and cosmetic.
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